Search results for "PEPTIDE RELEASE"

showing 2 items of 2 documents

Evidence for a role of inducible nitric oxide synthase in gastric relaxation of mdx mice

2006

Alterations of gastric mechanical activity have been reported in mdx mouse, animal model for Duchenne muscular dystrophy. This study examined if alterations in the vasoactive intestinal polypeptide (VIP) system are present in mdx stomach. Gastric mechanical activity was recorded in vitro as changes of endoluminal pressure and neurally or pharmacologically evoked relaxations were analysed in mdxvs normal stomach. Reverse-transcription polymerase chain reaction was used to detect inducible nitric oxide synthase (iNOS) expression. Relaxations to sodium nitroprusside in mdx stomach showed no difference in comparison with normal preparations. In normal stomach, VIP produced relaxation, which was…

Malemedicine.medical_specialtymdx mousePhysiologyMuscle RelaxationVasoactive intestinal peptideNitric Oxide Synthase Type IIStimulationDUCHENNES MUSCULAR-DYSTROPHYSettore BIO/09 - FisiologiaNitric oxidechemistry.chemical_compoundMiceOrgan Culture TechniquesInternal medicineQuinoxalinesmedicineAnimalsRNA MessengerEnzyme InhibitorsReceptorOxadiazolesbiologyEndocrine and Autonomic SystemsReverse Transcriptase Polymerase Chain ReactionStomachStomachGastroenterologySMOOTH-MUSCLE CELLSMuscle SmoothPEPTIDE RELEASENitric oxide synthaseMuscular Dystrophy DuchenneDisease Models AnimalEndocrinologymedicine.anatomical_structureNG-Nitroarginine Methyl Esterchemistrybiology.proteinMice Inbred mdxReceptors Vasoactive Intestinal PeptideSodium nitroprussideIminesmedicine.drugVasoactive Intestinal Peptide
researchProduct

MODIFIED PEPTIDE RELEASE FROM NEW IN SITU GEL FORMING COPOLYMERS BASED ON POLYLACTIDE AND POLYASPARTAMIDE

2008

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoPEPTIDE RELEASE GEL POLYASPARTAMIDE POLYESTER
researchProduct